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Sammie Winner Dr. Tom Waldmann of NIH discovers Cancer/AIDS treatments

November 6, 2009 - 1:15pm

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Meet Dr. Thomas Waldmann, winner of the 2009 Career Achievement Medal, the Sammie award that recognizes a federal employee for significant accomplishments throughout a lifetime of achievement in public service.

Dr. Waldmann is Chief of the Metabolism Branch for the National Institutes of Health (NIH), National Cancer Institute.

He has had a 52-year career making cutting-edge discoveries that have led to effective treatments for previously fatal forms of T-cell leukemia, Hodgkin's lymphoma, multiple sclerosis, various types of cancer and AIDS.

In 1955, Waldmann came to NIH after graduating from Harvard Medical School—and he never left. His seminal research has led to cutting-edge discoveries, including disorders of the elements that underlie leukemia and autoimmune diseases, when the body attacks its own cells.

Most significantly, Waldmann has created new treatments for previously fatal forms of leukemia and lymphoma and for multiple sclerosis.

He has been a creative pioneer in the field of cytokines—the molecules that control human immune responses—and developed the groundbreaking treatment Zenapax, which has since been associated with complete remission in over 60 percent of patients with Hodgkin's lymphoma that otherwise did not respond to any treatment.

Zenapax has also contributed to reducing the body's rejection of renal transplants, a discovery that majorly impacts the survival rate of patients.

He also found Zenapax therapy useful against autoimmune diseases, including multiple sclerosis, where he and his coworkers achieved a 78 percent reduction in new brain lesions.
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